Paternal age affects offspring via an epigenetic mechanism (2021.01.12)
Osumi Group has revealed a mechanism associated with an increased risk of behavioral defects among offspring of aged fathers in a mouse study. We examined the link between behavioral defects in mice, specifically animal communication, and decrease of DNA methylation - a major process controlling the expression of genes with a critical role in cell development, ageing and diseases such as cancer.
Press Release:
https://www.tohoku.ac.jp/en/press/age_father_affects_offspring_epigenetic_mechanism.html
EMBO Press Release:
https://www.embo.org/press-releases/age-of-father-affects-offspring-through-an-epigenetic-mechanism/
Article:
https://www.embopress.org/doi/full/10.15252/embr.202051524
Published in EMBO Reports
