Japanese

Tohoku University Graduate School of Medicine
Department of Developmental Neuroscience

PUBLICATION

Recent-publications

     
  • Thongkorn, S., Kanlayaprasit, S., Panjabud, P., Saeliw, T., Jantheang, T., Kasitipradit, K., Sarobol, S., Jindatip, D., Hu, VW., Tencomnao, T., Kikkawa, T., Sato, T., Osumi, N., Sarachana, T.: Sex differences in the effects of prenatal bisphenol A exposure on autism-related genes and their relationships with the hippocampus functions. Sci Rep. 11(1):1241, 2021. doi: 10.1038/s41598-020-80390-2.

    【Press Release】
    Tohoku University Press Release (2021.1.19)“Prenatal BPA Exposure May Contribute to the Male Bias of Autism Spectrum Disorder”

  • Yoshizaki, K., Kimura, R., Kobayashi, H., Oki, S., Kikkawa, T., Mai, L., Koike, K., Mochizuki, K., Inada, H., Matsui, Y., Kono, T., Osumi, N.: Paternal age affects offspring via an epigenetic mechanism involving REST/NRSF.EMBO Rep. 2021. e51524. doi: 10.15252/embr.202051524. 2021 Jan 5: Online ahead of print.

    【Press Release】
    Tohoku University Press Release (2021.1.5)“Age of Father Affects Offspring Through an Epigenetic Mechanism”

  • Casingal, C.R., Kikkawa, T., Inada, H., Sasaki, Y., Osumi, N.: Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis.Mol Brain 13(1):167, 2020. doi: 10.1186/s13041-020-00706-1.

    【Press Release】
    Tohoku University Press Release (2020.12.16)“New Insights into Fragile X Syndrome and the Fetal Brain”

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  • Kikkawa, T., Casingal, C, R., Chun, S, H., Shinohara, H., Hiraoka, K. and Osumi, N.: The role of Pax6 in brain development and its impact on pathogenesis of autism spectrum disorder. Brain Research. 1705, 95-103, 2019.
  • Mochizuki, K., Hayashi, Y., Sekinaka, T., Otsuka, K., Ito-Matsuoka, Y., Kobayashi, H., Oki, S., Takehara, A., Kono, T., Osumi, N. and Matsui, Y.: Repression of Somatic Genes by Selective Recruitment of HDAC3 by BLIMP1 Is Essential for Mouse Primordial Germ Cell Fate Determination. Cell Reports. 24(10), 2682-2693.e6, 2018.
  • Eguchi, K., Shindo, T., Ito, K., Ogata, T., Kurosawa, R., Kagaya, Y., Monma, Y., Ichijo, S., Kasukabe, S., Miyata, S., Yoshikawa, T., Yanai, K., Taki, H., Kanai, H., Osumi, N., Shimokawa, H.: Whole-brain low-intensity pulsed ultrasound therapy markedly improves cognitive dysfunctions in mouse models of dementia - Crucial roles of endothelial nitric oxide synthase. Brain Stimulation. 11(5), 959-973, 2018.
  • Kimura, R., Yoshizaki, K., Osumi, N.: Risk of Neurodevelopmental Disease by Paternal Aging: A Possible Influence of Epigenetic Alteration in Sperm. Developmental Origins of Health and Disease (DOHaD). Advances in Experimental Medicine and Biology. 1012, 75-81, 2018.
  • Maekawa, M., Watanabe, A., Iwayama, Y., Kimura, T., Hamazaki, K., Balan, S., Ohba, H., Hisano, Y., Nozaki, Y., Ohnishi, T., Toyoshima, M., Shimamoto, C., Iwamoto, K., Bundo, M., Osumi, N., Takahashi, E., Takashima, A., Yoshikawa T.
    Polyunsaturated fatty acid deficiency during neurodevelopment in mice models the prodromal state of schizophrenia through epigenetic changes in nuclear receptor genes. Transl Psychiatry. 7(9), e1229, 2017.
  • Nagasaki, M., Yasuda, J., Katsuoka, F., Nariai, N., Kojima, K., Kawai, Y., Yamaguchi-Kabata, Y., Yokozawa, J., Danjoh, I., Saito, S., Sato, Y., Mimori, T., Tsuda, K., Saito, R., Pan, X., Nishikawa, S., Ito, S., Kuroki, Y., Tanabe, O., Fuse, N., Kuriyama, S., Kiyomoto, H., Hozawa, A., Minegishi, N., Douglas Engel, J., Kinoshita, K., Kure, S., Yaegashi, N.; ToMMo Japanese Reference Panel Project, Yamamoto, M. Rare variant discovery by deep whole-genome sequencing of 1,070 Japanese individuals. Nat Commun. 6, 8018, 2015.
  • Tsunekawa, Y., Britto, J.M., Takahashi, M., Polleux, F., Tan, S-S. and Osumi, N.: Cyclin D2 in the basal process of neural progenitors is linked to non-equivalent cell fates. EMBO J. 31(8), 1879-1892, 2012.
Research@Tohoku University
Neuro Global Program Tohoku University
Brain and Individuality
Frontiers of Brain Science
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