Tohoku University Graduate School of Medicine
Department of Developmental Neuroscience


A new collaborative paper on gender difference in neuropathology of autism has come out (2021.02.05)

A paper by Surangrat Thongkorn, an internship student from Chulalongkorn University, has been published in Scientific Reports.

This paper clarified that the effects of intrauterine exposure to the endocrine disruptor bisphenol A are strongly expressed in male pup mice, and revealed some of the sex differences in the etiology and pathogenesis of neurodevelopmental disorders.
In the future, basic medical research that takes gender differences into account will become more important.

Publication Details:
Title: Sex differences in the effects of prenatal bisphenol A exposure on autism-related genes and their relationships with the hippocampus functions
Authors: Surangrat Thongkorn, Songphon Kanlayaprasit, Pawinee Panjabud, Thanit Saeliw, Thanawin Jantheang, Kasidit Kasitipradit, Suthathip Sarobol, Depicha Jindatip, Valerie W. Hu, Tewin Tencomnao, Takako Kikkawa, Tatsuya Sato, Noriko Osumi, and Tewarit Sarachana
Journal: Scientific Reports
DOI: 10.1038/s41598-020-80390-2

Press Release from Tohoku University:
Prenatal BPA Exposure May Contribute to the Male Bias of Autism Spectrum Disorder

Research@Tohoku University
Neuro Global Program Tohoku University
Brain and Individuality
Frontiers of Brain Science