■ 大隅 典子

■ 若松 義雄

■ 須藤文和

■ 高橋 将文

■ 沼山 恵子

高橋将文 2002-2008

■　英文原著

1) Takahashi, M and Osumi, N. Pax6 regulates specification of ventral neurone subtypes in the hindbrain by establishing progenitor domains. Development 2002 129: 1327-1338. 2) Kasai K, Takahashi M, Osumi N, Sinnarajah S, Takeo T, Ikeda H, Kehrl JH, Itoh G, Arnheiter H.The G12 family of heterotrimeric G proteins and Rho GTPase mediate Sonic hedgehog signalling. Genes Cells. 2004 Jan;9(1):49-58. 3) Kobayashi K, Takahashi M, Matsushita N, Miyazaki JI, Koike M, Yaginuma H, Osumi N, Kaibuchi K, Kobayashi K. Survival of Developing Motor Neurons Mediated by Rho GTPase Signaling Pathway through Rho-Kinase. J Neurosci. 2004 Apr 7;24(14):3480-3488. 4) Takahashi M and Osumi N. Identification of a novel type II classical cadherin: Rat cadherin19 is expressed in the cranial ganglia and Schwann cell precursors during development. Dev Dyn. 2005 232(1) :200-108. 5) Yokoo T, Ohashi T, Shen JS, Sakurai K, Miyazaki Y, Utsunomiya Y, Takahashi M, Terada Y, Eto Y, Kawamura T, Osumi N, Hosoya T. Human mesenchymal stem cells in rodent whole-embryo culture are reprogrammed to contribute to kidney tissues. Proc Natl Acad Sci U S A. 2005 Mar 1;102(9):3296-300. 6) Ogawa,Y., Takebayashi, H., Takahashi, M., Osumi, N., Iwasaki, Y. and Ikenaka, K. Gliogenic radial glial cells show heterogeneity in the developing mouse spinal cord. Dev Neurosci. 2005;27(6):364-77. 7) Sato K, Koizumi Y, Takahashi M, Kuroiwa A, Tamura K. Specification of cell fate along the proximal-distal axis in the developing chick limb bud. Development. 2007 134(7):1397-406. 8) Nomura, T. Takahashi, M, Hara, Y. and Osumi, N. Patterns of neurogenesis and amplitude of Reelin expression are essential for making a mammalian-type cortex. PLosOne, 3(1):e1454, 2008 9) Takahashi, M. and Osumi, N. Expression study of cadherin 7 and cadherin 20 in the embryonic and adult rat central nervous system. BMC. Dev. Biol. 8: 87, 2008

■　英文総説

1) Takahashi, M., Sato, K., Nomura, T. and Osumi, N. Manipulating gene expressions by electroporation in the developing brain of mammalian embryos. Differentiation 2002 70:155162. 2) Takahashi, M., Nomura, T. and Osumi, N. Transferring genes into cultured mammalian embryos by electroporation. Dev. Growth Differ. 2008 Aug;50(6):485-97

■　英文図書

1) Tsunekawa Y, Takahashi M and Osumi, N. Labeling of neuroepithelial cells using whole embryo culture and gene transfer methods to characterize the cell cycle. Bionanotechnology Based Future Medical Engineering Proceedings of the Tohoku University 21st Century Center of Excellence Programme (Eds M Esashi, K Ishii, N Ohuchi, N Osumi, M Sato, T Yamaguchi),203-210, 2007, Imperial College Press, London. 2) Takahashi M and Osumi, N. Live imaging of neuroepithelial cells in the rat spinal cord by confocal laser-scaninig microscopy. Bionanotechnology Based Future Medical Engineering Proceedings of the Tohoku University 21st Century Center of Excellence Programme (Eds M Esashi, K Ishii, N Ohuchi, N Osumi, M Sato, T Yamaguchi), 211-220, 2007, Imperial College Press, London.

■　和文総説

1) 高橋将文, 大隅典子 (2002). 哺乳類脳形成におけるPax6遺伝子の役割　「脳神経研究のフロンティア」実験医学増刊 20, 676-684. 2) 高橋将文、大隅典子(2008). 脳の領域化-特異的遺伝子発現とコンパートメント・境界形成の制御機構　蛋白質核酸酵素増刊 53 (4), 350-357.　神経の分化、回路、機能発現
■　和文図書
1) 高橋将文, 佐藤健一, 大隅典子 (2002). 哺乳類胚神経管および胎児脳への遺伝子導入法 遺伝子医学別冊：図で観る発生・再生医学実験マニュアル 22-35. 2) 高橋将文, 大隅典子 (2004). 神経系における細胞増殖・分化の制御「発生における細胞増殖制御」（竹内隆　岸本健雄編）77-85. 3) 高橋将文, 大隅典子 (2006). 免疫染色法の実際　注目のバイオ実験シリーズ　免疫染色＆in situ ハイブリダイゼーション　最新プロトコール　(野地澄晴編）103-127. 4) 高橋将文, 大隅典子 (2006). 写真撮影とデータ処理　注目のバイオ実験シリーズ　免疫染色＆in situ ハイブリダイゼーション　最新プロトコール　(野地澄晴編）165-197.
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