　 ■ 若松義雄

　若松義雄－２００８

　　　■　英文原著

1) S. Sawai, K. Kato, Y. Wakamatsu and H. Kondoh. Organization and expression of the chicken N-myc gene. Mol. Cell. Biol. 10, 2017-2026, 1990.

2) K. Kato, A. Kanamori, Y. Wakamatsu, S. Sawai and H. Kondoh. Tissue distribution of N-myc expression in the early organogenesis period of the mouse embryo. Dev. Growth Diff. 33, 29-36, 1991.

3) Y. Wakamatsu and H. Kondoh. Conditions for detection of embryonic N-myc Expression by in situ hybridization. Acta Histochem. Cytochem. 23, 367-374, 1991.

4) K. B. Avraham, B. C. Cho, D. Gilbert, H. Fujii, K. Okamoto, T. Shimazaki, T. Ito, H. Shoji, Y. Wakamatsu, H. Kondoh et al. Murine chromosomal location of four classIII POU transcription factors. Genomics 18, 131-133, 1993.

5) J. Goto, T. Miyabayashi, Y. Wakamatsu, N. Takahashi and M. Muramatsu. Organization and expression of mouse Hox3 cluster genes. Mol. Gene Gen. 239, 41-48, 1993.

6) D. Tomotsune, H. shoji, Y. Wakamatsu, H. Kondoh and N. Takahashi. A mouse homologue of the Drosophila tumor-supressor gene l(2)gl controlled by Hox-C8 in vivo. Nature 365, 69-72, 1993.

7) S. Sawai, A. Shimono, Y. Wakamatsu, C. Palmes, K. Hanaoka and H. Kondoh. Defects of embryonic organogenesis resulting from targeted disruption of the N-myc gene in the mouse. Development 117, 1445-1455, 1993.

8) Y. Wakamatsu, Y. Watanabe, A. Shimono and H. Kondoh. Transition of localization of the N-myc protein from nucleus to cytoplasm in differentiating neurons. Neuron 10, 1-9, 1993.

9) H. Shoji, T. Ito, Y. Wakamatsu, N. Hayasaka, K. Osaki, M. Oyanagi, R. Kominami, H. Kondoh and N. Takahashi. Regionalized expression of the Dbx family homeobox genes in the embryonic CNS of the mouse. Mech. Develop. 56, 25-39, 1996.

10) Y. Wakamatsu, Y. Watanabe, H. Nakamura and H. Kondoh. Regulation of the neural crest cell fate by N-myc: promotion of ventral migration and neuronal differentiation. Development 124, 1953-1962, 1997.

11) Y. Wakamatsu and J. A. Weston. Sequential expression and role of Hu RNA-binding proteins in neurogenesis. Development 124, 3449-3460, 1997.

12) Y. Wakamatsu, M. Mochii, K. S. Vogel and J. A. Weston. Avian neural crest-derived neurogenic precursors undergo apoptosis on the lateral migration pathway. Development 125, 4205-4213, 1998.

13) Y. Wakamatsu, T. M. Maynard, S. U. Jones and J. A. Weston. NUMB localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentitation by binding to NOTCH-1. Neuron 23, 71-81, 1999.

14) Wakamatsu Y, Maynard TM, Weston JA . Fate determination of neural crest cells by NOTCH-mediated lateral inhibition and asymmetrical cell division during gangliogenesis. Development 2000;127(13):2811-2821.

15) Thomas M. Maynard, Yoshio Wakamatsu and James A. Weston. Cell interactions within nascent neural crest cell populations transiently promote death of neurogenic precursors. Development 127, 4561-4572 , 2000.

16) Endo,Y., Osumi,N. and Wakamatsu, Y. Bimodal functions of Notch-mediated signaling are involved in neural crest formation during avian ectoderm development.Development 2002 129: 863-873

17) Endo,Y., Osumi, N, Wakamatsu, Y. Deltex/Dtx mediates NOTCH signaling in regulating Bmp4 expression for cranial neural crest formation during avian development. Dev Growth Differ. 2003 Jun;45(3):241-248.

18) Wakamatsu Y, Endo Y, Osumi N, Weston JA. Multiple roles of Sox2, an HMG-box transcription factor in avian neural
crest development. Dev Dyn. 2004 Jan;229(1):74-86

19) Wakamatsu Y, Osumi N, Weston JA.　Expression of a novel secreted factor, Seraf indicates an early segregation of Schwann cell precursors from neural crest during avian development.　Dev Biol. 2004 Apr 15;268(1):162-73.

20) Matsuda Y, Wakamatsu Y, Kohyama J, Okano H, Fukuda K, Yasugi S. Notch signaling functions as a binary switch for the determination of glandular and luminal fates of endodermal epithelium during chicken stomach development.
Development. 2005 Jun;132(12):2783-93.

21) Sakai D, Tanaka Y, Endo Y, Osumi N, Okamoto H, Wakamatsu Y. Regulation of Slug transcription in embryonic ectoderm by beta-catenin-Lef/Tcf and BMP-Smad signaling. Dev Growth Differ. 2005 Sep;47(7):471-82.

22) Tomita, Y., Matsumura, K., Wakamatsu, Y., Matsuzaki, Y., Shibuya, I.,Kawaguchi, H., Ieda, M., Kanakubo, S., Shimazaki, T., Ogawa, S., Osumi, N., Okano, H. and Fukuda, K. Cardiac neural crest cells as dormant multipotential stem cells in the mammalian heart. J Cell Biol. 2005 Sep 26;170(7):1135-46.

23) Sakai, D., Suzuki, T., Osumi, N., and Wakamatsu, Y. Cooperative action of Sox9, Snail2, and PKA signaling in early neural crest development. Development. 2006 Apr;133(7):1323-33.

24) Suzuki, T., Sakai, D., Osumi, N., Wada, H. and Wakamatsu, Y.　　Sox genes regulate type 2 collagen expression in avian neural crest
cells.　Develop. Growth Differ. 48, 477-486, 2006 Develop. Growth Differ. 48, 477-486, 2006

25) Wakamatsu, Y., Nakamura, N., Lee, J.A., Cole, G.J. and Osumi N. Transitin, a nestin-like intermediate filament protein, mediates cortical localization and the lateral transport of Numb in mitotic avian neuroepithelial cells. Development. 2007 Jul;134(13):2425-33.

　　　■　英文総説

1) Wakamatsu. Y. Understanding glial differentiation in vertebrate nervous system. Tohoku J. Exp. Med. 203, 233-240, 2004

2) Sakai, D. and Wakamatsu, Y. Regulatory mechanisms for neural crest formation Cells Tissues Organs 179 (1-2), 24-35, 2005

　　　■　英文図書

1) Nakamura N, Osumi, N and Wakamatsu Y. Time-lapse observation of neural epithelium cell behabior in slice culture. Bionanotechnology Based Future Medical Engineering Proceedings of the Tohoku University 21st Century Center of Excellence Programme (Eds M Esashi, K Ishii, N Ohuchi, N Osumi, M Sato, T Yamaguchi),145-150, 2007

2) Suzuki T, Sakai D, OSumi N and Wakamatsu Y. Expression of Sox9-interacting protein SC35/sfrs2 in avian embryos. Bionanotechnology Based Future Medical Engineering Proceedings of the Tohoku University 21st Century Center of Excellence Programme (Eds M Esashi, K Ishii, N Ohuchi, N Osumi, M Sato, T Yamaguchi),199-202, 2007

　　　■　和文総説

1) 若松義雄、近藤寿人：Ｎーｍｙｃ発現が制御する神経冠からの神経分化実験医学増刊「発生・神経研究の最前線'96-'97」14, 141-146, 1996

2) 近藤寿人、若松義雄、下野明彦：Ｎーｍｙｃ遺伝子と神経冠細胞の分化最新医学 51, 18-24, 1996

3) 若松義雄「道違えし者には死を給わんー神経冠細胞の分化と移動経路や細胞死との関係」．細胞工学 16, 263-268, 1997

4) 若松義雄：脊椎動物の神経分化と非対称分裂：NumbによるNotchシグナル制御細胞工学 18, 1322-1323, 1999

5) 若松義雄：脊椎動物神経発生における非対称分裂　「発生・神経研究の最前線2000」実験医学増刊 18, 9, 1270-1275, 2000

6) 若松義雄、大隅典子：神経堤細胞のボディプラン　「ボディープランと器官形成」現代化学増刊号　39、28-38, 2001

7) 若松義雄：発生過程に見る神経堤細胞のふるまいとその制御　「脳神経研究のフロンティア」実験医学増刊 20(5),2002, 715-722

8) 中村典子、若松義雄、大隅典子：中枢神経系の発生と発生異常　小児外科 35(3), 292-299,2003

9) 若松義雄：神経系幹細胞の非対称分裂　東北医学雑誌第116巻第1号（2004年6月）47-49

(10) 酒井大輔、若松義雄：神経堤形成のメカニズム　「発生システムのダイナミクス」　蛋白質核酸酵素増刊 Vol.50 No.6 684-691, 2005 共立出版　 Pub Med

(11) 若松義雄：Notchシグナル伝達の仕組みと役割、実験医学増刊「シグナル伝達研究2005-'06」68-75 羊土社　

（12) 若松義雄：神経堤細胞のEMTの制御、細胞工学27(4), 332-336, 2008

　　　■　和文図書

1) 若松義雄：リポフェクションによる鳥類神経冠細胞への遺伝子導入法. ニューロサイエンスラボマニュアル3「神経生物学研究に必要な胚と個体の遺伝子操作法」(近藤寿人　編集)　シュプリンガー・フェアラーク東京 pp 190-197, 1997

2) 若松義雄：わかる実験医学シリーズ　「発生生物学がわかる」第３章　神経堤細胞分化, p51-57 羊土社

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